![]() ![]() Even if the patient is taking the right dose of steroid for their condition, they may develop Cushing's syndrome. Prescription steroids called glucocorticoids, like prednisone, are used to treat patients who had a transplant or who have diseases such as rheumatoid arthritis, asthma, or inflammatory bowel disease. The main causes of Cushing's syndrome are ACTH-dependent disease (when the body makes too much ACTH which in turn increases the cortisol production), ACTH-independent disease (when the adrenal is making too much cortisol and the ACTH is therefore low), and iatrogenic disease (when the patient is taking prescription steroids). Although cortisol is essential to life, constantly high levels of cortisol can damage the entire body. ![]() A special part of the brain called the pituitary makes a hormone called adrenocorticotrophic hormone (ACTH) that controls the release of cortisol from the adrenal glands. Cortisol is necessary for daily life and helps the body respond to stressful events, regulates the sleep-wake cycles, and helps regulate the body's response to inflammation. Cortisol is a steroid that is made by the adrenal glands. Cushing's syndrome is a disease in which the body makes too much cortisol. ![]()
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